Genetic Inflammatory Factors Predict Restenosis After Percutaneous Coronary Interventions

Genetic inflammatory factors predict restenosis after percutaneous coronary interventions.

BACKGROUND Restenosis is a negative effect of percutaneous coronary intervention (PCI). No clinical factors are available that allow good risk stratification. However, evidence exists that genetic factors are important in the restenotic process as well as in the process of inflammation, a pivotal factor in restenosis. Association studies have identified genes that may predispose to restenosis, ...

Inflammation and restenosis after percutaneous coronary interventions.

The role of inflammation in the development of restenosis after percutaneous coronary interventions has been investigated in several studies. There is an interaction of inflammatory activation and vascular wall response to injury leading to intimal hyperplasia. Percutaneous interventions trigger inflammatory reactions leading to the development of intimal hyperplasia. This reaction is even more...

[Intracoronary inflammatory markers after percutaneous coronary interventions].

OBJECTIVE To analyze intracoronary release of inflammatory markers (IM) after percutaneous coronary interventions (PCI) and compare their concentrations concerning the type of PCI used (rotablator vs. balloon angioplasty). METHODS Twenty-two patients with average age of 60 +/- 11.9 years old, 12 of male sex, with stable coronary disease, submitted to elective treatment of a single coronary le...

Restenosis Rate After Multiple Percutaneous Transluminal Coronary

Background. Several studies suggest that repeated percutaneous transluminal coronary angioplasty procedures at the same site are associated with a progressively increasing risk of further restenosis and that short time intervals between successive procedures are predictive of future restenoses. Methods and Results. We assessed by quantitative coronary angiography the angiographic probability of...

In stent restenosis after percutaneous coronary intervention